Acanthamoeba are microscopic ameba commonly found in the environment. Acanthamoeba are ubiquitous organisms and have been isolated from soil, water, air, and dust. Acanthamoeba keratitis typically occurs in healthy persons. Most cases occur in people who wear contact lenses. The presence of Acanthamoeba in swimming pool water and the bacteriologic quality of the water have no correlation. Several species of Acanthamoeba have been found to infect humans, A. culbertsoni, A. polyphaga, A. castellanii, A. healyi, A. hatchetti, A. rhysodes, and possibly others. Acanthamoeba cysts are very resistant to chlorine. A higher percentage of isolates from swimming pools have been shown to be pathogenic than those isolated from natural fresh water.

Acanthamoeba have been establish in the nose and throat of robust folk as easily as those with compromised exempt systems. Acanthamoeba can participate the rind through a cut, injury, or through the nostrils. Once inside the system, amebas can move to the lungs and through the bloodstream to new parts of the system, particularly the key anxious structure. Through inappropriate warehousing, treatment, and disinfection of link lenses, Acanthamoeba can participate the heart and induce a severe transmission. Each year, many folk are infected with Acanthamoeba. Eye infections ensue from link lens cases becoming contaminated after inappropriate cleanup and handling. Risk of Acanthamoeba transmission is high for folk who take their own link lens cleaning resolution.

Most usually, Acanthamoeba are establish in the land and debris, in sweet water sources such as lakes, rivers, and warm springs and in warm tubs. Acanthamoeba may too be establish in brackish water and in ocean water. Amebas can also be found in Heating, Venting, and Air Conditioner units, humidifiers, dialysis units. Eye and skin infections are generally treatable. Eye infections may be prevented by using commercially prepared contact lens cleaning solution rather than making and using home made solutions. Acanthamoeba infections of the brain are almost always fatal. Because the cyst form may be highly resistant to therapy, a combination of agents is generally used. No clear consensus exists about use of steroids. Most authorities recommend that steroid use is probably best avoided. Patients receiving steroids should continue antiamebic therapy for several weeks after the steroids are stopped.