The Master of Science in Information Systems (MSIS) offered by American Sentinel University is a specialized program designed for information systems professionals who go on to manage the development, acquisition, implementation, and operation of information systems in a variety of organizational settings. The main aim of the online MS in Information Systems program is to produce graduates who are capable of becoming IT leaders. This is done through proper formulation and implementation of information systems that address organizational needs and provide decision support for top executives.

The program focuses on strategic skills needed to integrate an organization's information systems with its management goals by encompassing a broad spectrum of both information systems and advanced business courses. Additionally, the program addresses mission critical issues, such as strategic planning, risk management, financial consideration, project management, and quality assurance. The MS in Information Systems program is focused on the acquisition of information technology theory, but also the application of theory and practice to real world business opportunities and challenges.

Students enrolling in the program should have either a bachelor's degree in information systems, management, or a related field, or a bachelor's degree in a non-related field of study with significant IT-related work experience. Undergraduate prerequisite courses may be required depending upon an individual's background. Individuals enrolling in the program should also be self-motivated and interested in learning through a distance education program. The key objective of this program is to hone a student's communication, analytical and problem-solving skills. The courses lay a foundation for lifelong learning, professional development, research, or further graduate study.

The program emphasizes information systems theory and its application to business opportunities and challenges. The online MS in Information Systems program has been especially created for professionals who seek the skills and knowledge necessary to manage information systems resources in today's organizations. The program provides students with the necessary professional skills, conceptual frameworks, methods, technologies and hands-on experience of software development as a basis for a career in the IT industry. The program also includes specialized knowledge of specific IT topics and provides candidates with an opportunity to develop advanced research and/or development skills.

The program provides current theory and knowledge of essential information technology. While the courses examine a broad range of information technology resources, they also emphasize the management of such resources in order to meet an organization's goals.