Before I go any further it's necessary that I mention vitamin supplements are not a cure-all for all types of depression. For some people prescription drugs are necessary to manage their depression. However, vitamin supplements can still be very beneficial to those people, as well. It is always best to discuss the addition of any vitamins to your diet with your physician prior to making any changes. The balance of vitamins in your diet can sometimes be a delicate one. Add to that the fact that some vitamins may have an adverse reaction with certain medications and you can see why it's imperative to discuss the matter with your doctor.