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Apache The Definitive Guide

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The aim of treating acne is to stop new spots forming and many people may have unrealistic expectations of their treatments and therefore fail to comply with their treatment regimes. As everyone is so individual, it is not uncommon for one treatment to work well on one person, whilst another finds the same treatment may actually worsen their acne.



It is common for doctors to 'combine' a topical product (i.e. something applied directly to the skin) with an oral treatment (i.e. tablets taken by mouth).

TOPICAL TREATMENTS

Some of the creams or gels listed below can be irritant and may cause redness or soreness to the areas applied. Next to each type of treatment listed, we have coded it either

GSL, P, POM, HOM.

For your reference these abbreviations represent:

GSL = General Sales List. Freely available off the shelf. Can also be found in supermarkets or other non-pharmaceutical retail outlets.

P = Available over the counter, without a prescription, but not available off the chemist's shelf. It requires the supervision of a pharmacist.

POM = Prescription Only Medicine, only available upon production of a prescription.

HOM = Hospital Only Medicine. These can only be prescribed by a hospital consultant specialist.

Benzoyl Peroxide (P or POM)

Benzoyl Peroxide has been used for many years and doctors agree it can be an extremely effective treatment either used alone, or in combination with other prescription treatments. There is an argument that using Benzoyl Peroxide when using antibiotics can help reduce the problem of antibiotic resistance. It is very common to see a reaction on the skin, ranging from mild redness to, in exceptional cases, considerable peeling and soreness.

This is because the Benzoyl Peroxide causes a 'stripping' effect and when this happens, most people give up on it, thinking it isn't working. However, if you start with a low percentage (usually they come in 2.5%, 4%, 5% and 10% concentrations) then your skin may start to get used to it.

There are some types of Benzoyl Peroxide creams and gels that have been specially made to help combat the problem of excessive drying and redness. These products are mixed with a special ingredient that makes this problem less likely to happen. As a result, you may be able to start on a higher percentage of Benzoyl Peroxide.

Tip - Benzoyl Peroxide is used commercially for bleaching flour, it will also bleach hair or clothes. Therefore, use an old towel that can be kept specially for wiping hands after applying. Be aware of pillowcases and other bedclothes.

Topical Vitamin A Derivatives (POM)

Vitamin A derivatives have an effect on the cells which line the surface of the duct through which passes the grease from the grease glands and is therefore used where this duct is blocked. Its major effect is on the non-inflammatory lesion of acne (the blackheads and whiteheads). With regular use it reduces the number of blackheads and whiteheads. As the comedones usually precede inflamed spots, then this type of treatment can be very helpful.

Be aware that these types of creams should not be worn when in strong sunshine, as they can cause a sunburn reaction. Therefore it is advisable to apply at night and wash your skin in the morning. These preparations can be very irritating to the skin, so apply very sparingly (about the size of a pea for the face should be sufficient).

Adapalene (POM)

This is a fairly new type of retinoid-like gel cream. It can be very helpful on both inflamed and non-inflamed acne. Some patients report that it causes less irritation than some other topical creams.

Applied once daily.

Salicylic Acid (P or GSL)

The most commonly used topical agents include the antibiotics: tetracycline, erythromycin or clindamycin.

These are usually present in an alcoholic solution. They are sometimes mixed in a more soothing lotion format.

They are absorbed into the skin and help reduce the level of bacteria in the skin and in the duct as well as reducing inflammation commonly present around the spots themselves.

They are particularly useful in mild to moderate acne. The antibiotic should be applied twice a day (or as otherwise directed) to all affected areas, regardless of whether spots are present or not. Topical antibiotics when used alone have probably less effect on the non-inflamed type of spots (blackheads and whiteheads). If you have the non-inflammatory type of acne as well as red or yellow spots, a product such as isotretinoin or tretinoin (see

Topical vitamin A section above) could be used to help these.

In general, these types of antibiotics are very well tolerated by the skin and have few side effects.

Sensitive skin types may find the alcoholic solutions irritating to the skin and may cause excessive dryness.

Tip - Topical tetracycline is yellow when applied to the skin and can cause staining on clothes. It also fluoresces under ultra violet light; so don't apply before going to a disco, unless you want to resemble a glow-worm!

Combined Topical Antibiotics (POM)

As mentioned in the previous section, topical antibiotics can be very helpful in helping the redness and inflammation in acne. When the antibiotic is combined with another proven ingredient, it can help increase its benefits. Therefore, manufacturers have now developed some new treatments (available only on prescription) that can be of more benefit.

They may also reduce the resistance to the organism p.acnes. This is particularly true of erythomycin and zinc and erythromycin and benzoyl peroxide.

Erythromycin and Zinc (POM)

This topical lotion is available in two sizes. One for acne confined to a small area of the body, such as the face and neck, and the larger size to help more widespread acne. Zinc has been used for many years to help treat skin problems and in trials they have found the combined use of both zinc and erythromycin helps to reduce acne.

Tip - Ask the doctor for the larger size if your acne is also on your back, as it will go further. Once opened, each bottle can be used for 6 weeks, so there is little point in asking for the bigger size if you have it only on your face and neck as any unused lotion will have to be discarded after this time.
Apache The Definitive Guide
It is very common for patients to walk away with their prescription, products, and treatments only to give up on them too soon. TV adverts have persuaded too many influential teenagers that product X can clear spots in days!! Therefore a lack of compliance can contribute towards failure to treat acne effectively. Encouraging compliance can literally make the difference between scarred skin and emotional scars and someone who treats their skin and gets on with their lives. Therefore compliance can be encouraged in the following ways:

- Apply any topical treatments to all areas affected, every day - even when there are no spots. Many people will wait for a spot to appear before applying treatment and then, may be tempted to 'slap it on'. The aim of acne treatments is to avoid new spots forming and only regular, daily use of treatments will give the skin a chance to start reacting.

- Use any acne treatment for a minimum of two months. If, after this time, there is no significant improvement in the skin, then try another treatment. This TWO MONTH RULE applies to any treatment used for acne, including alternative and complementary medicine. Continue to use acne treatments until advised to stop by a doctor (prescription treatments only), or until you notice no further improvement. Never stop acne treatments suddenly, as this may cause a flare up of the skin.

- Some treatments may make the skin dry and flaky. It is perfectly acceptable to use an oil-free moisturiser to help counteract dryness. Allow treatments to absorb into the skin for approximately five minutes before applying moisturiser.

- Start off using creams or lotions just once a day, to build up tolerance. This may reduce the commonly heard complaint - 'It made my skin sore and red'

- Ensure medication is being used or taken correctly. For example, there is a huge amount of people that take oxytetracycline tablets with a cup of tea and as milk will inhibit the absorption of the drug, this makes the drug useless. Some treatments may need to be kept refrigerated or tablets taken with or without food. The pharmacist is able to help answer any concerns about how to take medication correctly.

What are the different types of acne?

The most common type of acne is called 'acne vulgaris' and is evident by the familiar spots, blackheads, whiteheads and greasy skin that affects up to 90% of the population at some time in their lives.

Acne is not necessarily a progressive disease - it may never be more than what a doctor would classify as mild, but a patient may end up suffering from this type of mild acne for 20 years or more. There have also been accounts of patients who have suddenly developed severe scarring acne within a matter of weeks.

Usually, treatments will depend upon the severity of the acne.

Acne - when should it start and when should it stop?

For some people, acne may last no longer than a few months, whilst others may be plagued for, in some cases, many decades. It is impossible to predict exactly how long acne will last. However, it may be an indicator that the acne could be persistent if either one or both of the two below has occurred:

- They had acne as a baby: This may be an indicator that the acne will return in early adolescence. In rare cases, it may never disappear from a baby, continuing well into late adult life. This type of acne, which occurs in babies or toddlers, is called infantile acne and can usually be treated with OTC topical creams. If the acne doesn't respond, they should consult a G.P.

- There is a family history of acne: Hereditary factors are a key to predicting who may be worse affected. Any close family relative may indicate a pre-disposition to developing acne, which may be stubborn and slow to respond to conventional acne treatments. These patients should seek treatment earlier and should be reminded to tell their GP about family history. This may make a difference to the type of treatment prescribed.

Acne may also persist well in the later years. SkinMed customers range in age from 10 to 80. This is unusual, but gives an idea how acne should not just be considered to be the bane of teenage life.

Possible reasons for people presenting with acne into their 30's could be:

- Polycystic ovarian syndrome (P.C.O.S.). See section on acne causes for further information.

- Stress. As we take on more responsibilities in our lives, so our levels of stress may have a 'knock-on' effect with our hormones. As we know, it is hormones responsible for acne and therefore, it is fair to assume that some people's hectic, stressful lives may indeed be a reason for a flare-up or outbreak of acne. De-stressing is an obvious answer to this particular problem, but it is not simple to change a lifestyle overnight. It is sensible to advise that this type of acne should still be treated appropriately with medication, whilst the person considers their lifestyle and changes they may need to make to help improve their acne.

- Coming off contraceptive pills. This may not be proven, but certainly some people report they have developed acne for the first time only since withdrawing from oral contraception.

Whatever the reason someone may have acne, they can still successfully treat it. There's simply no reason for someone to suffer the misery of acne - whatever their age.

CONTINUED IN PART 5
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