Growth hormone is a protein hormone. This is composed of about 190 amino acids that is synthesized and secreted by cells called somatotrophs in the anterior pituitary. It is a major participant in control of several complex physiologic processes, including growth and metabolism. Metabolism is also a crucial factor in fat burning and regulation of weight.
Several hormones are required for the proper functioning of growth process and this makes Growth a very complex process. Growth hormone stimulates the liver and other tissues to secrete IGF-I. IGF-I which stimulate proliferation of chondrocytes (cartilage cells), resulting in bone growth. Growth hormone does seem to have a direct effect on bone growth in stimulating differentiation of chondrocytes.
Muscle growth also seems to be a crucial issue here. IGF-I also appears to be the key player in muscle growth. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
So, overall Growth hormone has several important effects on protein, lipid and carbohydrate metabolism and the overall growth process of the body. Many studies have been done to analyze the effects of taking growth hormone and in many cases a direct effect of growth hormone has been observed with positive results. Production of growth hormone is modulated by many factors, including stress, exercise, nutrition, sleep and growth hormone itself. However, its primary controllers are two hypothalamic hormones and one hormone from the stomach. Human growth hormone was first used in treatment of underdeveloped children with success and later in short adults. Now, it has got a great deal to do with anti aging.
As is well known protein compounds are directly inter-related with growth hormones. Because growth hormone is made up of 191 amino acids, it makes sense to some people that additional amino acids might stimulate the synthesis and release of growth hormone.That is why it has become so popular especially among the bodybuilders and hard core strength trainers.Many scientific findings have confirmed that elevated HGH levels can have a very positive impact on just about every aspect of your life.
States of both growth hormone deficiency and excess provide very visible testaments to the role of this hormone in normal physiology. Such disorders can reflect lesions in either the hypothalamus, the pituitary or in target cells. A deficiency state can result not only from a deficiency in production of the hormone, but in the target cell's response to the hormone.
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