Diabetes mellitus is defined as a fasting blood glucose of 126 milligrams per deciliter (mg/dL) or more. "Pre-diabetes" is a condition in which blood glucose levels are higher than normal but not yet diabetic. Diabetes can cause many complications. Acute complications (hypoglycemia, ketoacidosis or nonketotic hyperosmolar coma) may occur if the disease is not adequately controlled. Serious long-term complications include cardiovascular disease (doubled risk), chronic renal failure (diabetic nephropathy is the main cause of dialysis in developed world adults), retinal damage (which can lead to blindness and is the most significant cause of adult blindness in the non-elderly in the developed world), nerve damage (of several kinds), and microvascular damage, which may cause erectile dysfunction (impotence) and poor healing. Poor healing of wounds, particularly of the feet, can lead to gangrene which can require amputation - the leading cause of non-traumatic amputation in adults in the developed world.
Diabetes is the third leading cause of death in the United States after heart disease and cancer. Over time, diabetes can lead to blindness, kidney failure, and nerve damage. These types of damage are the result of damage to small vessels, referred to as microvascular disease. Diabetes is also an important factor in accelerating the hardening and narrowing of the arteries (atherosclerosis), leading to strokes, coronary heart disease, and other large blood vessel diseases. This is referred to as macrovascular disease. Diabetes affects approximately 17 million people (about 8% of the population) in the United States. In addition, an estimated additional 12 million people in the United States have diabetes and don't even know it. Normally, blood glucose levels are tightly controlled by insulin, a hormone produced by the pancreas. Insulin lowers the blood glucose level.
Non-insulin-dependent diabetes mellitus (NIDDM)-is due to a combination of defective insulin secretion and insulin resistance or reduced insulin sensitivity (defective responsiveness of tissues to insulin), which almost certainly involves the insulin receptor in cell membranes. In the early stage the predominant abnormality is reduced insulin sensitivity, characterized by elevated levels of insulin in the blood. Gestational diabetes also involves a combination of inadequate insulin secretion It develops during pregnancy and may improve or disappear after delivery. Even though it may be transient, gestational diabetes may damage the health of the fetus or mother, and about 20%-50% of women with gestational diabetes develop type 2 diabetes later in life.Gestational diabetes mellitus (GDM) occurs in about 2%-5% of all pregnancies.
What Is Diabetes Mellitus
Diabetes mellitus is blood sugar is high chaotic is unusual because the body does not produce enough insulin l '. Normally, levels of blood glucose are tightly controlled by insulin, a hormone produced by the pancreas. The insulin lowers blood glucose levels. When a student blood glucose, insulin is secreted by the pancreas to normalize blood sugar. In patients with diabetes, the absence or insufficient production of insulin causes high blood sugar. Diabetes is the leading cause of blindness in adults non-elderly, the leading cause of non-traumatic amputation in adults, and diabetic kidney disease is the leading kidney disease requiring dialysis the USA. Therefore, insulin deficiency or insensitivity of its receptors plays a central role in all forms of diabetes mellitus.
Grave or recurrent pancreatitis and other diseases that directly damage the pancreas can lead to diabetes. As indicated above, in patients with diabetes, insulin is either absent, relatively insufficient for the needs of the body, or not used properly by the body. All these factors cause high levels of glucose in the blood. People with diabetes May experience numerous and serious, long-term complications. Some of these complications begin in the months following the onset of diabetes, although most tend to develop after a few years. Most complications are progressive. High levels of blood sugar spill glucose in urine. People with diabetes often develop bacterial and fungal infections, typically of the skin. When sugar levels in the blood are high, white blood cells can not fight effectively against infections.
Diabetes can cause many complications. The strong can prevent complications if the disease is not adequately controlled. Diabetes mellitus is characterized by disordered metabolism and too high blood sugar is caused by low levels of the hormone insulin or abnormal insulin resistance effects associated with inadequate secretion insulin to compensate. Diabetes is also an important factor in accelerating the hardening and narrowing of the arteries, which leads to strokes, heart disease and other major diseases of the blood vessels. This is known as macrovascular disease. The characteristic symptoms are excessive production of urine, excessive thirst and increased liquid, and blurred vision. These symptoms may be absent if blood sugar is slightly elevated. Poor healing of wounds, especially feet, can lead to gangrene, requiring amputation May.
Diabetes mellitus is now an old type of illness, did not address, and the medical service must be essential to the emphasis is to avoid possible short-and long-term problems associated with diabetes. Diabetes screening is recommended for many people in various stages of life, and for those with one or more risk factors. The test varies depending on circumstances and local policies, May and be a random blood glucose, a fasting blood sugar test or a more formal test of glucose tolerance. An adequate treatment of diabetes, and putting more emphasis on blood pressure control and lifestyle, May improve the risk profile of complications above. Another treatment option is the use of insulin pump with some of the most popular pump brands: Cozmo, animas, Medtronic MiniMed and omnipod.
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